Welcome to ChemBioServer
This Server is part of the Bioacademy Bioserver that hosts a group of tools and web services developed in the Biomedical Research Foundation of the Academy of Athens.
Its main aim is to facilitate computational compound screening and analysis and it is funded by the Greek Ministry of Education Cooperation Proposal Entitled as PIK3CA Oncogenic Mutations in Breast and Colon Cancers: Targeted Development of Anticancer Drugs.
Please cite the program as:
ChemBioServer: a web-based pipeline for filtering, clustering and visualization of chemical compounds used in drug discovery. Athanasiadis E., Cournia Z., Spyrou G. Bioinformatics. 2012 Nov 15;28(22):3002-3. Epub 2012 Sep 8. http://dx.doi.org/10.1093/bioinformatics/bts551
Before using ChemBioServer please ensure that:
A PDF reader is localy installed.
Server has been tested and worked properly on:
Windows XP, Vista, 7.
Ubuntu (version 12.04).
Mac OS X Leopard (version 10.5).
using latest versions of:
This Server provides the following services:
Uploading and Browsing Compounds in 2D and 3D.
Filtering of compounds based on physicochemical properties.
Substructure filtering of compounds based on custom sdf files.
Van der Waals filtering using distance and energy tests.
Toxicity filtering using specific organic toxic roots.
Hierarchical clustering with 4 different distances.
Affinity Propagation clustering, providing exemplars for each cluster.
Creating custom pipeline filtering.
Visualization of compounds' properties.
Launched on Dec 30th, 2011 Updated on June 20th, 2012
© 2011 BioAcademy |
BioAcademy: Biomedical Researh Foundation Academy of Athens |